华南师范大学生命科学学院副研究员,硕导。西安交通大学学士,新加坡国立大学博士、博士后。从事环境与人体微生物组研究,应用多组学技术与微生物学手段探究微生物抗生素耐药基因的环境过程与传播机制。以通讯或第一作者在Nature Medicine,Nature Microbiology,Nature Communications, ISME Journal等期刊发表SCI论文20余篇,H-index为16。主持国自然面上项目、青年项目、广东省自然面上项目等。
论文专著(1第一作者,# 通讯作者):
1. Globally distributed mining-impacted environments are underexplored hotspots of multidrug resistance genes. Yi X1, Liang JL1, Su JQ, Jia P, Lu JL, Zheng J, Wang Z, Feng SW, Luo ZH, Ai HX, Liao B, Shu WS, Li JT# and Zhu YG. The ISME Journal (2022) 16: 2099-2113.(ESI高被引论文)
2. Giant viruses as reservoirs of antibiotic resistance genes. Yi X1, Liang JL1, Wen P, Jia P, Feng WS, Liu SY, Zhuang YY, Guo YQ, Lu JL, Zhong SJ, Liao B, Wang Z, Shu WS and Li JT#. Nature Communications (2024) 15: 7536.(入选期刊Editors’ Highlights文章)
3. The airway microbiome mediates the interaction between environmental exposure and respiratory health in humans. Lin L1, Yi X1, Liu H1, Meng R1, Li S, Liu X, Yang J, Xu Y, Li C, Wang Y, Xiao N, Li H, Liu Z, Xiang Z, Shu WS, Guan WJ#, Zheng XY#, Sun JF# and Wang Z#. Nature Medicine (2023) 29: 1750-1759.(入选2023年中国传染领域十大进展)
4. Multi-omics analyses of airway host–microbe interactions in chronic obstructive pulmonary disease identify potential therapeutic interventions. Yan Z1, Chen BX1, Yang YQ1, Yi X1, Wei MY1, Ecklu-Mensah G, Buschmann MM, Liu H, Gao J, Liang W, Liu X, Yang J, Ma W, Liang Z, Wang F, Chen D, Wang L, Shi W, Stampfli MR, Li P, Gong S, Chen X, Shu WS, EI-Omar EM, Gilbert JA, Blaser MJ, Zhou H#, Chen R# and Wang Z#. Nature Microbiology (2022) 7: 1361-1375.(ESI高被引论文)
5. The human lung microbiome—a hidden link between microbes and human health and diseases. Yi X, Gao J and Wang Z#. iMeta (2022) e33.
近三年其它论文:
1. Phytostabilization mitigates antibiotic resistance gene enrichment in a copper mine tailings pond. Yi X1, Wen P1, Liang JL, Jia P, Yang TT, Feng SW, Liao B, Shu WS and Li JT#. Journal of Hazardous Materials (2023) 443: 130255.
2. Environmental exposure, airway microbiome and respiratory health: You are what you breathe. Yi X, Cai H, Gao J, Wang Z#. Clinical and Translational Medicine (2023) 13(9): e1394.
3. Differential airway resistome and its correlations with clinical characteristics in Haemophilus- or Pseudomonas-predominant microbial subtypes of bronchiectasis. Yi X1, Yang JH1, Huang Y1, Han XR1, Li HM1, Cen LJ, Lin ZH, Pan CX, Wang Z#, and Guan WJ#. Respiratory Research (2023) 24, 264.
4. Characteristics of upper and lower respiratory tract microbiota after lung transplantation. Cai Y, Fan Y, Chen A, Wang X, Wang L, Chen J, Wang Z, Li J#, Yi X# and Ju C#. Respiratory Research (2025) 26(1): 160.
5. Inflammatory endotype-associated airway resistome in chronic obstructive pulmonary disease. Yi X1, Li Y1, Liu HY1, Liu X, Yang J, Gao J, Yang Y, Liang Z, Wang F, Chen D, Wang L, Shi W, Lam DCL, Stampfli MR, Paul WJ, Chen R# and Wang Z#. Microbiology Spectrum (2022) 10(2): e02593-02521.
6. Sputum microbiota compositions correlate with metabolome and clinical outcomes of COPD-bronchiectasis association: a prospective cohort study. He ZF1, Zhang XX1, Pan CX1, Yi X1, Huang Y, Chen CL, Zha SS, Cen LJ, Cai HQ, Yang L, Gao JQ, Li HM, Lin ZH, Lin SZ, Wang Z#, Zhong NS#, Guan WJ#. Exploration (2025) 20240149.