江锦祥,心理学博士,助理研究员,硕士研究生导师。本硕毕业于广州医科大学,博士就读于华南师范大学。主要从事阿尔茨海默病、社会行为紊乱、躯体感觉异常和情绪障碍等脑疾病相关神经机制研究。以第一或通讯作者在J Neurosci、Brain Behav Immun、J Alzheimers Dis、ACS Chem Neurosci、Exp Neurol等国际神经科学期刊发表成果。主持国家自然科学基金青年项目、广东省自然科学基金面上项目、国家博士后基金等课题,现任广东省生物物理学会青年专业委员会常务委员。
论文专著(#第一作者,*通讯作者):
1. Chen M, Wang J, Jiang J, Zheng X, Justice NJ, Wang K, Ran X, Li Y, Huo Q, Zhang J, Li H, Lu N, Wang Y, Zheng H, Long C* and Yang L*. APP modulates KCC2 expression and function in hippocampal GABAergic inhibition. eLife 2017; 6 2017/01/06. DOI: 10.7554/eLife.20142.
2. Jiang J#, Liu H#, Huang Z, Cui Y, Zhang X*, Zhang X, Cui Y* and Xin W*. The role of CA3-LS-VTA loop in the formation of conditioned place preference induced by context-associated reward memory for morphine. Addict Biol 2018; 23: 41-54. 2016/11/20. DOI: 10.1111/adb.12468.
3. Zahra A, Jiang J, Chen Y, Long C* and Yang L*. Memantine rescues prenatal citalopram exposure-induced striatal and social abnormalities in mice. Exp Neurol 2018; 307: 145-154. 2018/06/19. DOI: 10.1016/j.expneurol.2018.06.003.
4. Zhang J#, Hao C#, Jiang J#, Feng Y, Chen X, Zheng Y, Liu J, Zhang Z, Long C* and Yang L*. The mechanisms underlying olfactory deficits in apolipoprotein E-deficient mice: focus on olfactory epithelium and olfactory bulb. Neurobiol Aging 2018; 62: 20-33. 2017/11/07. DOI: 10.1016/j.neurobiolaging.2017.09.036.
5. Jiang J#, Zheng Y, Chen Y, Zahra A, Long C* and Yang L*. Exposure to prenatal antidepressant alters medial prefrontal-striatal synchronization in mice. Brain Res 2019; 1717: 27-34. 2019/04/16. DOI: 10.1016/j.brainres.2019.04.008.
6. Chen M#, Chen Y#, Huo Q#, Wang L, Tan S, Misrani A, Jiang J, Chen J, Chen S, Zhang J, Tabassum S, Wang J, Chen X, Long C* and Yang L*. Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models. Molecular neurodegeneration 2021; 16: 14. 2021/03/06. DOI: 10.1186/s13024-021-00434-7.
7. Misrani A#, Tabassum S#, Huo Q#, Tabassum S#, Jiang J#, Ahmed A, Chen X, Zhou J, Zhang J, Liu S, Feng X, Long C* and Yang L*. Mitochondrial deficits with neural and social damage in early-stage Alzheimer's disease model mice. Front Aging Neurosci 2021; 13: 748388. Original Research 2021/12/28. DOI: 10.3389/fnagi.2021.748388.
8. Peng Y#, Cai P, Hu J, Jiang J*, Zhang J, Liu K, Yang L* and Long C*. Altered corticostriatal synchronization associated with compulsive-like behavior in APP/PS1 mice. Exp Neurol 2021; 344: 113805. 2021/07/10. DOI: 10.1016/j.expneurol.2021.113805.
9. Yu W#, Wu X#, Chen Y#, Liang Z#, Jiang J, Misrani A, Su Y, Peng Y, Chen J, Tang B, Sun M, Long C, Shen J* and Yang L*. Pelvic pain alters functional connectivity between anterior cingulate cortex and hippocampus in both humans and a rat model. Front Syst Neurosci 2021; 15: 642349. Original Research 2021/06/22. DOI: 10.3389/fnsys.2021.642349.
10. Jiang J#, Tang B#, Wang L#, Huo Q#, Tan S#, Misrani A, Han Y, Li H, Hu H, Wang J, Cheng T, Tabassum S, Chen M, Xie W, Long C* and Yang L*. Systemic LPS-induced microglial activation results in increased GABAergic tone: A mechanism of protection against neuroinflammation in the medial prefrontal cortex in mice. Brain Behav Immun 2022; 99: 53-69. 2021/09/29. DOI: 10.1016/j.bbi.2021.09.017.
11. Shen J#, Li M#, Long C, Yang L* and Jiang J*. Altered odor-evoked electrophysiological responses in the anterior piriform cortex of conscious APP/PS1 mice. J Alzheimers Dis 2022; 90: 1277-1289. 2022/10/18. DOI: 10.3233/JAD-220694.
12. Ghouse M#, Li M#, Long C* and Jiang J*. Multichannel extracellular recording in freely moving mice. J Vis Exp 2023: e65245. 2023/06/12. DOI: 10.3791/65245.
13. Jiang J#, Tan S, Feng X, Peng Y, Long C* and Yang L*. Distinct ACC neural mechanisms underlie authentic and transmitted anxiety induced by maternal separation in mice. The Journal of neuroscience: the official journal of the Society for Neuroscience 2023; 43: 8201-8218. 2023/10/17. DOI: 10.1523/JNEUROSCI.0558-23.2023.
14. Tan S#, Jiang J, Huang H, Mo X, Feng J, Chen Y, Yang L* and Long C*. Neural mechanism underlies CYLD modulation of morphology and synaptic function of medium spiny neurons in dorsolateral striatum. Frontiers in molecular neuroscience 2023; 16: 1107355. Original Research 2023/02/28. DOI: 10.3389/fnmol.2023.1107355.
15. Misrani A#, Tabassum S#, Wang T#, Huang H, Jiang J, Diao H, Zhao Y, Huang Z, Tan S, Long C* and Yang L*. Vibration-reduced anxiety-like behavior relies on ameliorating abnormalities of the somatosensory cortex and medial prefrontal cortex. Neural Regen Res 2024; 19: 1351-1359. 2023/10/31. DOI: 10.4103/1673-5374.385840.
16. Li M#, Liu K#, Xu M, Chen Z, Yu L, Zhang J, Wang C, Long C* and Jiang J*. Anterior cingulate cortex-anterior insular cortex circuit mediates hyperalgesia in adolescent mice experiencing early life stress. ACS Chem Neurosci 2025 2025/02/17. DOI: 10.1021/acschemneuro.4c00884.