生命科学学院
School of Life Sciences
任充华
- 性别：男
- 职称：研究员
- 学历：博士
- 学科：生物化学与分子生物学
- 工作电话：
- 电子邮件：renchonghua111@m.scnu.edu.cn
- 相关链接：http://www.scholat.com/chren
- 简历更新：2021-04-25
研究员。西北农林科技大学-美国加州大学戴维斯分校联合培养博士，2017年作为师资博后入职华南师范大学，于2019年初作为青年拔尖人才留校任教并受聘为副教授（副高），2021年受聘为研究员（正高），获批广东省杰出青年基金，并入选“广东省百名博士博士后创新人物”创新样本集萃。
作为第一作者和通讯作者（含共一或共通讯）在Trends in Biotechnology、Nucleic Acids Research、Cellular and Molecular Life Sciences (2篇)、Nature Communications、Insect Science、Journal of Insect Physiology等国际知名刊物上发表论文多篇，授权国家发明专利5项；主持国家自然科学基金面上项目/青年项目、广东省自然科学基金杰青项目/面上项目、博士后科学基金面上项目、广州市自然科学基金面上项目等。
担任Elsevier出版集团丛书审稿人，Nucleic Acids Research、Molecular Therapy、Molecular Therapy- Methods & Clinical Development, Frontiers in Bioengineering and Biotechnology、Frontiers in Genetics、Biochemistry、 Scientific Reporters等SCI期刊审稿人。
代表性论文专著(#第一作者，*通讯作者，按时间倒序)：
1 Zheng Zhao#, Liang Li#, Min Cheng#, Andi Jing, Suning Liu, Shiming Zhu, Erxia Du, Sheng Li, Yunxia Luan*, Chonghua Ren*. Grh signaling regulates epithelium development and ecdysis in Blattella germanica. Insect Science. 2020.27(2) (DOI: 10.1111/1744-7917.12780) (中科院一区Top)
2 Chonghua Ren#, Kun Xu#, David Jay Segal, Zhiying Zhang*. Strategies for the enrichment and selection of genetically modified cells. Trends in Biotechnology. 37(1) 2019 pp. 56-71 (一区Top, 5/232位, IF=13.578)
3 Na Li#, Mei Zeng#, Huilu Xiao#, Shuren Lin#, Shuting Yang#, Haixin Huang, Shiming Zhu, Zheng Zhao, Chonghua Ren#, Sheng Li#. Alteration of insulin and nutrition signal gene expression or depletion of Met reduce both lifespan and reproduction in the German cockroach. Journal of Insect Physiology 2019, 118:103934
4 Sheng Li#*, Shiming Zhu#, Qiangqiang Jia#, Dongwei Yuan#, Chonghua Ren#, Kang Li, Suning Liu, Yingying Cui, Haigang Zhao, Yanghui Cao, Gangqi Fang, Daqi Li, Xiaoming Zhao, Jianzhen Zhang, Qiaoyun Yue, Yongliang Fan, Xiao-Qiang Yu, Qili Feng, and Shuai Zhan*. The genomic and functional landscapes of developmental plasticity in the American cockroach. Nature Communications. 2018. 2018, 9(1): 0-1008. (JCR: Q1, IF=12.353)
5 Chonghua Ren, Alexa Adams, Benjamin Pyles, Barbara J. Bailus, Henriette O’Geen, David J. Segal*. In-vivo applications of cell-penetrating zinc finger transcription factors. In: Liu J. (eds) Zinc Finger Proteins. Methods in Molecular Biology, vol 1867. Humana Press, New York, NY ISBN:978-1-4939-8799-3
6 Henriette O’Geen, Chonghua Ren, Nicole Coggins, David J. Segal*. Unexpected binding behaviors of bacterial Argonautes in human cells cast doubts on their use as targetable gene regulators. Plos One. 2018. 13(3): e0193818. doi: 10.1371/journal. pone.0193818
7 Yichun Bai, Yang Liu, Zhenlei Su, Yana Ma, Chonghua Ren, Runzhen Zhao, Honglong Ji*. Gene editing as a promising approach for respiratory diseases. Journal of Medical Genetics. 2017. 10.1136/jmedgenet-2017-104960 (IF=5.45)
8 Henriette O’Geen#, Chonghua Ren#, Charles M. Nicolet, Andrew A. Perez, Julian Halmai, Victoria M. Le, Joel P. Mackay, Peggy J. Farnham and David J. Segal*. dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression. Nucleic Acids Research. 2017. DOI: 10.1093/nar/gkx578 (JCR: Q1, IF=11.561)
9 Simin Shao, Chonghua Ren, Zhongtian Liu, Yichun Bai, Zhilong Chen, Zehui Wei, Xin Wang, Zhiying Zhang*, Kun Xu*. Enhancing CRISPR/Cas9-mediated homology-directed repair in mammalian cells by expressing Saccharomyces cerevisiae Rad52. International Journal of Biochemistry and Cell Biology. 92 (2017) 43–52 (IF=3.9)
10 Yun Wu, Kun Xu, Chonghua Ren, Xinyi Li, Huijiao LU, Furong Han, Zehui Wei, Xin Wang, Zhiying Zhang*. Enhanced CRISPR/Cas9-mediated biallelic gene editing with dual-surrogate reporter system. FEBS Letter. 2017. DOI: 10.1002/1873-3468.12599 (IF=3.519)
11 Chonghua Ren#, Kun Xu#, Zhongtian Liu, Juncen Shen, Furong Han, Zhilong Chen, Zhiying Zhang*. Dual-reporter surrogate systems for efficient enrichment of genetically modified cells. Cellular and Molecular Life Sciences. 2015. 72(14), p. 2773-4 (JCR: Q1, IF=5.856)
12 Kun Xu#, Chonghua Ren#, Zhongtian Liu, Tao Zhang, Tingting Zhang, Duo Li, Ling Wang, Qiang Yan, Lijun Guo, Juncen Shen, Zhiying Zhang*. Efficient genome engineering in eukaryotes using Cas9 from Streptococcus thermophilus. Cellular and Molecular Life Sciences. 72 (2) (2014), pp. 383–399 http://dx.doi.org/10.1007/s00018-014-1679-z (JCR: Q1, IF=5.856, 2014 Global Medical Discovery 'Key scientific article')
13 Chonghua Ren#, Qiang Yan, Zhiying Zhang*. Minimum length of direct repeat sequences required for efficient homologous recombination induced by zinc finger nuclease in yeast. Mol Biol Rep. 2014 Oct; 41(10):6939-48. doi: 10.1007/s11033-014-3579-6 (IF=2.024)
14 刘素宁，李胜，任充华*. CRISPR系统用于昆虫基因表达调控的研究进展与展望。 昆虫学报。2018 61(12):1481-1487.
授权发明专利：
1 任充华，李胜。一种dsRNA及其在防治德国小蠊上的应用。发明专利，申请或专利号：201810775922.8 (授权时间：2019.06.11)
2 任充华，李胜。美洲大蠊断肢再生相关Wingless信号通路基因及其dsRNA的应用。发明专利，申请或专利号：201810775847.5(授权时间：2019.05.28)
3 李胜，任充华。美洲大蠊断肢再生相关Hedgehog信号通路基因及其dsRNA的应用。发明专利，申请或专利号：201810883915.X(授权时间：2019.07.12)
4 任充华，李胜，赵政。与德国小蠊表皮发育相关的Cad96ca基因、该基因的dsRNA及其制备方法与应用。发明专利，专利号：201910976989.2 (授权日期2020.09.01)
5 李胜，任充华，赵政。与德国小蠊表皮发育相关的Grh基因、该基因的dsRNA及其制备方法与应用。发明专利，申请或专利号：201910977154.9 (授权日期2020.11.10)
6 张智英，白义春，徐坤，魏泽辉，和林洁，任充华，邵斯旻，吴芸，刘中天。一种利用CRISPR/Cas9技术基于SSA修复的基因无缝编辑方法。发明专利，专利号: 201610333062.3