近5年的主要论文列表(^#第一作者，^*通讯作者)：

（1） Wucheng Yang, Yu Xie, Chaowan Guo, Zedong Ouyang, Chuanxia Jiang, Xiaolin Chen, Jian Wei, Jianhua Tan*, Ruifang Fan*. Sunscreens with Nicotinamide As Skin-Brightening Ingredient Increase Exposure Risk of UV-filters: Quantitative Analysis of UV-filters Skin Penetration Based on an Improved in vivo Confocal Raman Spectroscopy Method. Environmental Science & Technology, 2025, 59, 20978−20989.(IF₂₀₂₄=11.3) 

（2） Jian Liu#, Yuxin chen#, Hao Pu, Xiaolin Chen, Wucheng Yang, Zedong Ouyang, Qihua Pang, Ruifang Fan*. A new mechanism involved in cardiovascular senescence induced by environmental relevant dose of 16 priority-controlled PAHs. Environment International, 2025, 197:109326. (IF₂₀₂₄=9.7)

（3） Zedong Ouyang, Weiwei Zhu, Wucheng Yang, Yuqing Xie, Jian Liu, Qihua Pang, Ruifang Fan*. Green tea diet can effectively antagonize the toxicity induced by environmental related concentrations of BPA: an implication from an in vivo and in silico study. Journal of Agricultural and Food Chemistry, 2024， 72(37):20225-20704. (IF₂₀₂₄=5.7, 一区，封面文章) 

（4） Lingxue Meng, Zedong Ouyang, Yuxin Chen, Chengmeng Huang, Yunjiang Yu, Ruifang Fan^*_. Low-dose BPA-induced abnormal neuronal energy metabolism and apoptosis mediated by PINK1/parkin mitophagy pathway in juvenile rats, Science of the Total Environment, 2024, 929:172655. (IF₂₀₂₄=8.0)

（5） Jian Liu, Jiaying He, Zengquan Liao, Xiaolin Chen, Yufeng Ye, Qihua Pang, Ruifang Fan*. Environmental doses of 16 priority-controlled PAHs induce endothelial dysfunction: an in vivo and in vitro study. 2024, Science of the Total Environment, 2024, 919, 170711. (IF₂₀₂₄=8.0)

（6） Lingxue Meng, Shiheng Gui, Zedong Ouyang, Yajuan Wu, Youling Zhuang, Qihua Pang, Ruifang Fan^*, Low dose bisphenols sex-specifically induce neurodevelopmental toxicity in juvenile rats and the antagonism of EGCG, Journal of Hazardous Materials, 2023, 459:132074. (IF₂₀₂₃=12.2)

（7） Lei Wang, Chengmeng Huang, Leizi Li, Qihua Pang, Congcong Wang, Ruifang Fan*. In vitro and in silico assessment of GPER-dependent neurocytotoxicity of emerging bisphenols. Science of the Total Environment, 2023, 862, 160762. (IF₂₀₂₃=8.2)

（8） Wucheng Yang, Jianglu Feng, Wenyao Liang, Mingxia Nie, Jianhua Tan*, Ruifang Fan*. A high- throughput method for the determination of 14 UV-filters in human plasma by LC-MS/MS: minimize interference from proteins and phospholipids, Journal of Chromatography B, 2024,1237:124090. (IF₂₀₂₃=2.8)

（9） Hongxuan Kuang, Yonghong Li, Leizi Li, Shengtao Ma, Taicheng An*, Ruifang Fan*. Four-year population exposure study: Implications for the effectiveness of e-waste control and biomarkers of e-waste pollution. Science of the Total Environment, 2022, 42:156595. (IF₂₀₂₂=9.8).

（10） Congcong Wang, Lei Wang, Chengmeng Huang, Yungang Liu, Qihua Pang, Hongyu Han, Ruifang Fan*. Involvement of NLRP3-/Caspase-1-/GSDMD- dependent pyroptosis attenuates BPA-induced apoptosis of neuroblastoma cells. Biochemical Pharmacology，2022, 200:11542. (IF₂₀₂₂=5.8）

（11） Jiaying He#, Qihua Pang#, Chengmeng Huang, Jiaqi Xie, Jindian Hu, Lei Wang, Congcong Wang, Lingxue Meng, Ruifang Fan*. Environmental dose of 16 priority-controlled PAHs mixture induces vascular endothelial cells dysfunction through oxidative stress. Toxicology in Vitro, 2022, 79:105296. (IF₂₀₂₂=3.2)

（12） Hongxuan Kuang, Zhilin Li, Jianglu Feng, Jianhua Tan, Wangqi Zhu, Shengjie Lin, Qihua Pang, Ruifang Fan*. Volatile organic compounds from second-hand smoke may increase susceptibility of children through oxidative stress damage. Environmental Research, 2022, 207：112227. （IF₂₀₂₂=8.3）

（13） Jianhua Tan^#, Hongxuan Kuang^#, Xuejing Lv, Yingwei Zeng, Wenji Zhou, Qilai Xie *, Ruifang Fan*. Distribution characteristics and health risk assessment of a novel antibacterial alternative in personal care products: chloroxylenol. Science of the Total Environment, 2021, 786, 147524. (IF₂₀₂₁=10.753）

（14） Hongxuan Kuang, Zhilin Li, Xuejing Lv, Peiqiong Wu, Jianhua Tan, Qiurong Wu, Wenhui Jiang, Qihua Pang, Ruifang Fan*. Exposure to volatile organic compounds may be associated with oxidative DNA damage-mediated childhood asthma. Ecotoxicology and Environmental Safety, 2021, 210: 111864. (IF₂₀₂₁=7.129)

（15） Congcong Wang, Jiaying He, Tongfei Xu, Hongyu Han, Zhimin Zhu, Lingxue Meng, Qihua Pang*, Ruifang Fan*. Bisphenol A(BPA), BPS and BPB-induced oxidative stress and apoptosis mediated by mitochondria in human neuroblastoma cell lines, Ecotoxicology and Environmental Safety, 2021, 207:111299. (IF₂₀₂₁=7.129，SCI高被引文章)

（16） Hongxuan Kuang, Jian Liu, Yingwei Zeng, Wenji Zhou, Peiqiong Wu, Jianhua Tan, Yonghong Li, Qihua Pang, Wenhui Jiang^*, Ruifang Fan*. Co-exposure to polycyclic aromatic hydrocarbons, benzene and toluene may impair lung function by increasing oxidative damage and airway inflammation in asthmatic children. Environmental Pollution, 2020, 266,115220. (IF₂₀₂₀=8.071)

（17） Haibin Zhang, Zhouyu Wang, Lingxue Meng, Hongxuan Kuang, Jian Liu, Xuejing Lv, Qihua Pang, Ruifang Fan^*, Maternal exposure to environmental bisphenol A impairs the neurons in hippocampus across generations, Toxicology, 2020, 432:152393. (IF₂₀₂₀=4.221)

专利：

1. 范瑞芳，液相色谱串联质谱分析尿液中苯和甲苯四种代谢产物的方法，授权专利号：ZL-201310067770.3，授权日期：2014年4月2日。（已转让)

2. 范瑞芳，王磊，一种快速评估双酚类化合物神经毒性的方法，ZL-20220401145.5，授权日期：2024年8月16日。

博士研究生去向：

2021届  王丛丛 广州大学环境科学与工程学院

2021届  邝洪轩 生态环境部华南生态环境科学研究所

2023届  孟令雪 生态环境部华南生态环境科学研究所

2024届  刘  剑 广东省农业科学研究院植物保护研究所

招生信息

本实验室热忱欢迎热爱科学研究的优秀学生报考博士生和硕士生。常年招收环境毒理学、公共卫生流行病学以及环境科学方向的博士后和青年英才。请有意者将个人简历通过电子邮件发至：20001047@m.scnu.edu.cn来信请注明申请方向及职位。