相辉,女,研究员,博士生导师。2000年本科毕业于西北大学,2003年硕士毕业与中国科学院西双版纳热带植物园,2008年于中国科学院上海植物生理生态研究所获得博士学位,2010年于中国科学院昆明动物研究所博士后出站,随后在中科院昆明动物研究所遗传资源与进化国家重点实验室任副研究员,项目研究员。2011年入选首批“中国科学院青年创新促进会”会员。2016年作为青年拔尖人才加入华南师范大学。主要以基因组学研究手段,联合基因编辑等功能分析,深入开展昆虫表型适应性演化机制研究。以第一或通讯(含共同)作者在Nature Biotechnology,Nature Ecology and Evolution,Molecular Biology and Evolution、Communications Biology、Zoological Research等期刊发表论文30多篇,获得授权专利8项。主持973计划课题、国防科技创新特区项目、国家自然科学基金面上项目、中国科学院“西部之光人才培养计划” 重点项目等。获得省级自然科学奖(二等,排名第二)及省级优秀科技论文奖(特等,排名第一)。担任昆虫学会基因组学专业委员会委员,任Zoological Research 编委成员。参编科学出版社《分子生物学》教材一部,指导本科生获得全国大学生生命科学竞赛国家级一等奖。
论文专著(#第一作者,*通讯作者):
第一或通讯作者论文:
1. Xiang H#,Liu XJ#, Li MW#,Zhu YN, Wang LZ, Cui Y, Liu LY, Fang G, Qian HY, Xu AY*, Wang W* and Zhan S*. 2018.The evolutionary road from wild moth to domestic silkworm. Nature Ecology and Evolution 2(8): 1268-1279.
2. Cui Y#, Fang GQ#, Zhong J#, Bai XR#, Xue H#, Yi MY, Chen BZ, Zhu YN, Wang W, Liu YQ*, Zhan S*, Xiang H*. Divergent and convergent evolution underlie the cocoon-spinning diversity. The Innovation Life. (In press)
3. Zhu KS#, Yu GZ#, Wang Y, Li ZQ, Hu FY, Zhai JJ, Lin LG, Peng CL, Ren YD*, Xiang H*, Gao L* . 2025. The Eichhornia genomes illuminate the aquatic adaptation of the invasive water hyacinth. Plant,Cell & Environment. (Accepted)
4. Wei XM, Cui Y, Lin YJ, Xiang JH, Zhu KS, Xiang H*, Wang M*. 2025. Comprehensive transcriptomics comparison reveals switch of gene networks in the brain during silkworm domestication. Insect science. DOI 10.1111/1744-7917.70077
5. Wang M#, Lin YJ#, Fu ZY#, Xi Wu, Mang J, Cheng YL, Gao YL, Xue H, Du EX, Chen JH, Feng QL, Xiang H*. 2025. Insufficient wing development possibly contributes to flightlessness of the silkworm Bombyx mori during domestication. Proceedings of the Royal Society B. 292: 20250281
6. Yi M#, Yang X#, Wang M, Chen J, Xiang J, Xiang L, Qian L, Chen D, Huang Y, Tong X*, Liu Z*, Xiang H*. 2025. Consistence, distinction and possible metabolic crosstalk of the nitrogen motivation related genes in affecting silk production and silk gland biology. Zoological Research. 46(2):446-458
7. Zuo DS#, Liu WW#, Zhao RP, Kesen Zhu KS, Wang W*, Xiang H*. 2025. Drosophila CG11700 may not affect male fecundity-lifespan tradeoff as previously reported. Molecular Biology and Evolution 42(2): msaf003
8. Liu X, Zhang ZJ,Hu B, Chen K, Yu Y, Xiang H*, Tan AJ*. 2024. Single-cell transcriptomes provide insights into expansion of glial cells in Bombyx mori. Insect Science 31(4):1041-1054
9. Xu H#, Chen L#, Tong XL#, Hu H, Liu LY, Liu GC, Zhu YN, Zhao RP, Wang W, Dai FY*, Li X*, Xiang H*. 2022. Comprehensive silk gland multi-omics comparison illuminates two alternative mechanisms in silkworm heterosis. Zoological Research 43(4): 585-596.
10. Wang Z#, Zhu K#, Li H, Gao L, Huang H, Ren Y*, Xiang H*. 2022. Chromosome‐level genome assembly of the black widow spider Latrodectus elegans illuminates composition and evolution of venom and silk proteins. GigaScience 11:1-11
11. Wu, C#, Wang DF#, Niu KK, Feng QL, Chen HW, Zhu HB*, Xiang,H*.2021. Gene expression profiling in peripheral blood lymphocytes for major depression: preliminary cues from Chinese discordant sib-pair study. Translational Psychiatry 11(1): 540..
12. Cui, Y#., Liu ZL#, Li CC#, Wei XM, Lin YJ, You L, Zhu ZD, Deng HM, Feng QL*, Huang YP* and Xiang H*. 2021. Role of juvenile hormone receptor Methoprene-tolerant 1 in silkworm larval brain development and domestication. Zoological Research 42(5): 637-649.
13. Wu F#, Niu KK#, Cui Y#, Li CC, Lyu M, Ren YD, Chen YF, Deng HM, Huang LH, Zheng SC, Liu L, Wang J, Song QS*, Xiang H*, Feng QL*. 2021. Genome-wide analysis of DNA G-quadruplex motifs across 37 species provides insights into G4 evolution. Communications Biology 4: 98
14. Zhou SY, Dong QL, Zhu KS, Gao L*, Chen X*, Xiang H*. 2021. Long-read transcriptomic analysis of orb-weaving spider Araneus Ventricosus indicates transcriptional diversity of spidroins. International Journal of Biological Macromolecules 168(31): 395-402
15. Wang M#, Lin YJ#, Zhou SY, Cui Y, Feng QL, Yan W*, Xiang H* . 2020. Genetic mapping of climbing and mimicry: two behavioral traits degraded during silkworm domestication. Frontiers in Genetics 11: 566961
16. Cui Y#, Ren YD#, Lyu M, Zheng SC, Feng QL, Xiang H*. 2020. Genomic divergences between the two polyphagous Spodoptera relatives provide cues for successful invasion of the fall armyworm. Insect Science 27: 1257-1265
17. Zhu YN#, Wang LZ#, Li CC, Cui Y, Wang M, Lin YJ, Zhao RP, Wang W, Xiang H*. 2019. Artificial Selection on Storage Protein 1 Possibly Contributes to Increase of Hatchability during Silkworm Domestication. Plos Genetics 15(1): e1007616
18. Cui Y#, Zhu YN#, Lin YJ, Chen L, Feng QL, Wang W*, Xiang H*. 2018. New insight into the mechanism underlying the silk gland biological process by knocking out fibroin heavy chain in the silkworm. BMC Genomics 19: 215
19. Dong Y, Dai FY, Ren YD, Liu H, Chen L, Yang PC, Liu YQ, Li X, Wang W*, Xiang H*. 2015. Comparative transcriptome analyses on silk glands of six silkmoths imply the genetic basis of silk structure and coloration. BMC genomics 16: 203
20. Xiang H#,Zhu JD#, Chen Q#, Dai FY#, Li X#, et al. Xia YQ*, Wang W*, Wang J*. 2010. Single base-resolution methylome of the silkworm reveals a sparse epigenomic map. Nature Biotechnology 28 : 516
获奖:
1. 2011,云南省科技论文奖特等奖 排名第一(相辉,王文,李昕,张国捷,董扬)
2. 2017. 家蚕等鳞翅目昆虫茧丝进化机制及基因资源挖掘 云南省自然科学二等奖 排名第二(王文,相辉,李昕,陈垒,董扬)
专利:
1. 崔勇,相辉,冯启理; 鳞翅目昆虫酪氨酸蛋白激酶在防治虫害中的应用, 2021.02.09, 中国, ZL201810557603.X.
2. 朱克森,相辉,董庆林,周世怡,陈新; 云斑蛛牵引丝性能及其丝蛋白基因序列, 2021.01.26, 中国, ZL201910497633.0.
3. 周世怡,相辉,朱克森,董庆林,陈新; 大腹园蛛牵引丝性能及其丝蛋白基因序列, 2021.02.19,中国, ZL201910498175.2.
4. 林永坚,相辉,冯启理 ; 一种野蚕幼虫的饲养方法, 2020.09.18, 中国, ZL201710725547. 1.