生命科学学院
School of Life Sciences
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2017-05-18 23:16:48 来源:华南师范大学生命科学学院 点击: 收藏本文
刘琳, 华南师范大学生命科学院,副教授,硕士生导师
2002/9-2006/04 香港中文大学,生物系,博士,导师:葛伟教授
1992/09-1995/07 华南师范大学,生物系,硕士,导师:张剑英教授
1985/09-1989/07 青岛海洋大学,水产学院,学士
科研与学术工作经历 :
2014/09-2016/06 美国密西根大学,生化、分子、发育系,访问学者,合作导师:段存明
2007/5-今, 华南师范大学生命科学院,副教授, 硕士导师
2006/5-2007/4 香港中文大学,生物系,研究助理,合作导师:葛伟
1995/8-2002/8 华南师范大学生物系,助教,讲师
1989/7-1992/8:在四川省水产研究所从事科研工作。参加农业部课题鱼病课题1项
主持或参加科研项目(课题)及人才计划项目情况:
主持科研项目:
1. 国家自然科学基金,面上项目:斜纹夜蛾精巢融合的分子调控研究( 31772519)(2018.1-2021.12)60万 主持,在研
2. 广东省自然科学基金,面上项目:整合素integrin在斜纹夜蛾精巢融合中的功能研究(2017A030313210)(2017.5-2020.5)10万 主持,在研
3. 广东省海洋与渔业发展专项资金科技攻关与研发 高效健康养殖与病害防治技术:本尼登虫全虫灭活疫苗的制备及免疫原性的测定 (2017.8-2019.8)50 万 主持,在研
4. 广东省自然科学基金面上项目:斜纹夜蛾精巢融合的发育生物学作用 (S2012010010185) (2012.10-2014.10)5万 主持,已结题
5. 广东省自然科学基金,博士启动:卵母细胞特异生长因子GDF9在斑马鱼性腺分化发育中的作用 (8451063101000345)(2008.10-2010.10) 3万,主持,已结题
6. 家蚕基因组生物学国家重点实验室开放基金资助课题:家蚕转录因子POUM2对丝蛋白合成的调节研究 (2013.1-2014.12)(sklsgb2013003)20万,主持(因出国访学,申请延缓结题)
参加科研项目
7. 国家自然科学基金国际(地区)合作交流项目:DNA G4和i-motif高级结构对昆虫基因表达的表观遗传调控 (主持人:冯启理) ( 31720103916)
(2018.01-2022.12)244万,排第二,在研
8. 国家自然科学基金重点项目:家蚕翅原基变态发育的分子调控机理 (主持人:冯启理)(31330071)(2014.01-2018.12)301万,排第二,在研
9. 国家自然科学基金重大项目: 动物志,单殖吸虫II编写(主持人:张剑英)(31093430)(2011.01-2015.12),41万,最后校稿阶段;负责英文摘要、英文检索及鳞盘科等近80种的描述
10. 国家自然科学基金面上项目:多盘类单殖吸虫的区系分类研究 (主持人:丁雪娟)(30570222)(2006.1-2008.12),已结题
11. 国家自然科学基金面上项目:中国海洋鱼类单殖吸虫区系分类研究 (主持人:丁雪娟)(30270184)(2003.1-2005.12),已结题
12. 广东省渔港建设和渔业发展专项资金:本尼登虫疫苗研究(I).本尼登虫的转
录组研究及免疫相关基因开发 (主持人:丁雪娟)(2016.8-2017.8)30 万,
申请结题
代表性研究成果和学术奖励情况:
一、期刊论文
1. 第一作者论文
1、刘琳,冯启理. 鳞翅目昆虫精巢融合的研究 (2014). 华南师范大学自然科学版 46:1-6
2、Chen WT, Liu L#, Ge W. 2017. Expression Analysis of Growth Differentiation Factor 9 (Gdf9/gdf9), Anti-Müllerian Hormone (Amh/amh) and Aromatase (Cyp19a1a/cyp19a1a) during Gonadal Differentiation of the Zebrafish, Danio rerio Biology of Reproduction 96(2): 401-413 DOI:https://boi.org/10.1095/bioreprod.116.144964 , bio144564 03Feb2017
2. 通讯作者论文
3、Du Q, Wen L, Zheng SC, Bi HL, Huang YP, Feng QL and Liu L* 2018
Identification and functional characterization of doublesex gene in the
testis of Spodoptera litura Insect Science 00, 1–11, DOI 10.1111/
1744-7917.12608
4、陈亚青、夏亭、郑思春、冯启理、刘琳*, 2017.斜纹夜蛾视黄酸结合蛋白(Slcrabp)基因的克隆、表达及功能的研究.环境昆虫学报, 39(3):493-504
5、Ou J, Deng HM, Zheng SC, Huang LH, Feng QL*, Liu L.* (2014) Transcriptomic analysis of developmental features of Bombyx mori wing disc during metamorphosis. BMC Genomics,15:820 (IF:3.8)
6、欧俊,郑思春,冯启理,刘琳* (2013) 果蝇翅原基发育分化的主要过程及分子机理. 昆虫学报 56(8):917-924
7、Yuan Q, Xiao Z, Ding XJ, and Liu L*(2013) Two new species of mazocraeid monogeneans from Clupanodon punctatus (Temminck & Schlegel) (Clupeiformes: Clupeidae) found in Daya Bay, South China Sea, with the proposal of Chelimazocraes n. g. Systematic Parasitology. 86:271-283.
8、Huang Z, Zhou D, Gao G, Zheng S, Feng Q, Liu L*(2012)Cloning and characterization of a midgut-specific fatty acid binding protein in Spodoptera litura. Arch insect biochem and Physiol 79:1-17
9、Zhan Q, Zheng S, Feng Q, and Liu L* (2011) A midgut-specific chymotrypsin cDNA (SlCTLP1) from Spodoptera litura: Cloning, characterization, localization and expression analysis. Arch insect biochem and Physiol 76(3):130-143
10、Cao SM, Ding XJ, Zhang JY, and Liu L* (2010) Monogenea of Chinese Marine Fishes. Xviii.Two monocotylids, including a new species, from the blotched fantail ray Taeniurops meyeni (Elasmobranchii: Dasyatidae) in the South China Sea. Folia Parasitologica. 57:169-172.
3. 既非第一作者又非通讯作者论文
11、Niu KK, Zhang XJ, Deng HM, Wu F, Ren Y, Xiang H, Zheng SC, Liu L, Huang LH, Zeng BJ, Li S, Xia QY, Song QS, Palli SR, Feng, QL*., 2017. BmILF and i-motif structures are involved in transcriptional regulation of BmPOUM2 in Bombyx mori. Nucleic Acids Research, doi: 10.1093/nar /gkx1207. (IF 10.162)
12、He Y, Deng HM*, Hu QH, Zhu ZD, Liu L, Zheng SC, Song QS, and Feng QL*. (2017) Identification of the binding domains and key amino acids for the interaction of the transcription factors BmPOUM2 and BmAbd-A in Bombyx mori. Insect Biochemistry And Molecular Biology, 81:41-50.
13、Duan CM and Liu L,. (2015) It takes two gonadotropins to tango in zebrafish but with a mixed tune. Endocrinology, 156(10): 3490–3493.
14、Gu J, Huang LX, Gong YJ, Zheng SC, Liu L, Huang LH*, and Feng QL.(2013) De novo characterization of transcriptome and gene expression dynamics in epidermis during the larval-pupal metamorphosis of common cutworm. Insect Biochemistry And Molecular Biology. 43:794-808.
15、Rao ZC*, He WY, Liu L, Zheng SC, Huang LH, and Feng QL.(2012), Identification, Expression and Target Gene Analyses of MicroRNAs in Spodoptera litura. PloS one. 7.
16、Deng HM, Zhang JL, Li Y, Zheng SC, Liu L, Huang LH, Xu WH, Palli SR, Feng, QL*. (2012). Homeodomain POU and Abd-A proteins regulate the transcription of pupal genes during metamorphosis of the silkworm, Bombyx mori. PNAS 109: 12598-12603
17、Liu J, Zheng S, Liu L, Li L, Feng QL. (2010). Protein profiles of the midgut of Spodoptera litura larvae at the sixth instar feeding stage by shotgun ESI-MS approach. J Proteome Res 9:2117-2147.
18、Deng HM, Zheng SC, Yang X, Liu L, Feng QL. (2011). Transcription factors BmPOUM2 and BmbetaFTZ-F1 are involved in regulation of the expression of the wing cuticle protein gene BmWCP4 in the silkworm, Bombyx mori. Insect Mol Biol 20:45-60.
19. Shen Y, Gu J, Huang LH*, Zheng SC, Liu L, Xu WH, Feng QL, and Kang L, (2011). Cloning and expression analysis of six small heat shock protein genes in the common cutworm, Spodoptera litura. J Insect Physiol 57:908-914.
20. Tang L, Zhang C, Liu L, Feng QL, and Zheng SC* (2011). Cloning and expression of the nuclear transcription factor Sl ss FTZ-F1 cDNA from Spodoptera litura. Insect Science.18:635-644
21、Zhang C, Zhou DH, Zheng SC, Liu L, Tao S, Yang L, Hu S, Feng QL. (2010). A chymotrypsin-like serine protease cDNA involved in food protein digestion in the common cutworm, Spodoptera litura: Cloning, characterization, developmental and induced expression patterns, and localization. J Insect Physiol 56:788-799
22、Liu JS, Zheng SC, Liu L, Li L*, and Feng QL. (2010). Protein Profiles of the Midgut of Spodoptera litura Larvae at the Sixth Instar Feeding Stage by Shotgun ESI-MS Approach. Journal Of Proteome Research. 9:2117-2147.
23、Guo XR, Zheng SC, Liu L, and Feng QL.* (2009). The sterol carrier protein 2/3-oxoacyl-CoA thiolase (SCPx) is involved in cholesterol uptake in the midgut of Spodoptera litura: gene cloning, expression, localization and functional analyses. BMC Molecular Biology.10.
24、Zhang JY, Yang TB, Liu L, Ding XJ (2003). A list of monogeneans from Chinese marine fishes. Systematic Parasitology. 54:111-130.
25、Zhang JY, Liu L, Fang JP Ding XJ (2003). Monogenea from the middle Yangtze Valley: Sinomazocraes changjiangensis n. g., n. sp (Family Mazocraeidae Price, 1936) on a clupeiform fish from Hubei Province, China. Systematic Parasitology. 54:103-109.
26、Wang WB, Liu L, Zhou YX (2003). Description of four new species of Haliotrema Johnston & Tiegs (Monogenea, Ancyrocephalidae). Acta Zootaxonomica Sinica. 28:24-29.(in Chinese)
27、Ding XJ, Pan J, Liu L. (2003). Monogenea of Chinese marine fishes a new species of Monaxinoides from fishes of the South China Sea (Mazocraeidea, Monaxinoididae). Acta Zootaxonomica Sinica. 28:606-609. (in Chinese)
28、Zhang JY, Liu L, Ding XJ, Chen ZB. (2000) Monogenea of Chinese marine fishes XI. Two new species of the genus Diplectanum diesing, 1858. Acta Hydrobiologica Sinica.;24:150-154. (in Chinese)
29、Zhang JY, Ding XJ, Liu L, Wang JY(1999). Monogenea of Chinese marine fishes. X. A new species and two new records of the Axinidae from fishes of the south China Sea. Systematic Parasitology. 43: 7-10.
30、Zhang JY, Ding XJ, Pang QH, Lin Liu. (1998)Two new species of the family Mazocraeidae Price, 1936 (Monogenea) on clupeiform fishes from Guangdong, China. Systematic Parasitology. 41:115-122.
31、 Jianying Zhang, Lin Liu, Xuejuan Ding(1997). Monogenea of Chinese marine fishes. VII. A new species and two new records of the Tetraonchoididae from fishes of the South China and East China Seas. Systematic Parasitology. 38:197-201.
二、会议论文
1. 第一作者论文
1、Liu, L., Ma, Q., Liu, Y., Feng, Q. Fusion of testis is beneficial to male reproduction in Spodoptera litura (Lepidoptera). 3rd biennial conference of the North American Society for Comparative Endocrinology Ottawa, Ontario, Canada, 2015,June 21-25
2. 通讯作者论文
2、Ma YZ, Wu Q, Liu YC, Feng QL, Liu L* Morphology, structure, transcriptomics and regulation of testis fusion in Spodoptera litura 第五届国际昆虫生理生化与分子生物学学术研讨会(IPBMB), Guangzhou, P.R. China, 2015.6.15-18
三、授权发明专利
廖铭炯,郑思春,刘琳,冯启理农药微胶囊颗粒剂及其制备方法 2013.6.12,中国, 2009101924951
刘琳、冯启理、万星、张丽丽、郑思春、梁丽宁 斜纹夜蛾固醇转运蛋白稳定转化的细胞株及其制备方法和应用 中国 申请号:201610935108.9
四、会议报告
刘琳,斜纹夜蛾精巢融合的研究,昆虫动物学会年会,昆明,2016.10.10-13
五、专著
张剑英,杨廷宝,刘琳等著 中国海洋鱼类单殖吸虫 北京:农业出版社,2001 , 6 p.1-400
张剑英,邱兆祉,丁雪娟等编著 鱼类寄生虫与寄生虫病 北京:科学出版社 1999,6 p.1-735(参加第3、5、7、8章的编著)